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Differentials for Common EKG findings

EKG FindingDifferentials
RAD (Right Axis Deviation)Normal Variation: vertical heart with an axis of 90º
Right Ventricular Hypertrophy (RVH)
Right heart strain (e.g. PE)
Left Posterior Fascicular Block
Pre-excitation Syndrome (Wolff-Parkinson-White)
Lateral Wall Myocardial Infarction
LAD (Left Axis Deviation)Normal Variation
Left ventricular hypertrophy
Left bundle branch block
Left anterior fascicular block
Pre-excitation syndromes (Wolff-Parkinson-White)
Inferior wall myocardial infarction
Early R-wave progressionPosterior MI
RVH
RBBB
WPW
Poor R-wave progressionAnterior MI
LVH
RVH
Cor-pulmonale
Important differentials for Q wavesMI
LVH
RVH
Cor-pulmonale (Q waves in inferior and anterior leads)
Cardiomyopathy
Important ST-T changesNon-specific ST-T changes: < 1 mm ST elevation/ depression; flat T- waves or < 1 mm inversion of T- waves
MI/ Angina
Pericarditis
Early repolarization
Juvenile T waves
LVH: ST depression and T- inversion, typically in I, aVL, V5, V6. Can be seen in other leads as well
RVH: ST depression and T- inversion, typically in V1-3
Bundle Branch blocks
Persistent ST- elevation (Usually present for over 3 weeks): Consider ventricular aneurysm
Peaked T-wavesHyperkalemia
MI
Intracranial bleed
LVH/ RVH
LBBB
Deep T-wavesMI
Intracranial bleed
LVH/ RVH
Takusubo cardiomyopathy
Apical Hypertrophic cardiomyopathy
Digoxin
ST elevation in aVR with ST depression in multiple leads: suspect 3 vessel disease or left main disease
Short QTcHypercalcemia, Hyperkalemia, Congenital
Long QTcDrugs
Antiarrhythmics: IA, IC, III
Antipsychotics, tricyclics
Methadone
Antibiotics: Floroquinolones, Macrolides
Fluconazole
Most antiemetics
Hypocalcemia (T- waves usually normal)
Hypomagnesemia
Hypokalemia
Congenital
Important differentials for U-wavesHypokalemia
Hypothermia
Bradyarrhythmias
Drugs (e.g., digoxin, class IA, and class III anti-arrhythmics)
Electrical alternansPericardial effusion
Tachyarrhythmias
Severe CHF/ CAD/ HTN
Inverted P-QRS-T in I and aVL and upright in aVRDextrocardia (shows reverse R wave progression)
LA/RA lead reversal (Shows normal R- progression)
In WPW pattern, be cautious diagnosing the following on EKGVentricular hypertrophy
MI and ischemia (since WPW can cause Q-waves and ST-T changes)
Axis deviation
Any other conduction abnormalities

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